Great Plains Chapter of the American College of Cardiology

Latest in Cardiology from ACC.org

• compariSon of secOnd-generation seLf-expandable vs. balloon-expandable Valves and gEneral vs. local anaesthesia in Transcatheter Aortic Valve Implantation
  The goal of the SOLVE-TAVI trial was to compare the safety and efficacy of the Edwards Sapien S3 valve vs. Medtronic’s CoreValve among patients undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. Further, in a 2x2 factorial design, the trial also sought to compare conscious sedation vs. general anesthesia in this patient population.
• Immune Checkpoint Inhibitors and Venous Thromboembolism
  Does an early rise in C-reactive protein (CRP) levels during immune checkpoint inhibitor (ICI) therapy predict the risk of venous thromboembolism (VTE) in cancer patients?
• Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy
  The goal of the VALOR-HCM trial was to assess the safety and efficacy of adding mavacamten to maximally tolerated medical therapy among patients with obstructive hypertrophic cardiomyopathy (HCM).
• Papillary Muscle Structural Abnormalities and Site of Origin of Arrhythmias
  Does the finding of structural abnormalities on the papillary muscles have an association with site of origin of arrhythmias? Can multimodality imaging be of benefit in planning ablation procedures?
• A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity
  The goal of the SUMMIT trial was to compare the safety and efficacy of tirzepatide among patients with heart failure with preserved ejection fraction (HFpEF) and obesity.